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Other less common but reportable concerns include gallbladder issues (right upper abdominal pain, especially after fatty meals), signs of hypoglycemia if you are on concurrent diabetes medications, and kidney problems indicated by changes in urination or swelling in the legs

Combinations of GLP-1 with other entero-pancreatic hormones with complementary actions and/or synergistic potential (such as glucose-dependent insulinotropic polypeptide (GIP), glucagon, and amylin) are under investigation to enhance the weight loss and cardiometabolic benefits of GLP-1 RA [21]

It mimics endogenous GLP-1, slowing gastric emptying, suppressing glucagon, and increasing glucose-dependent insulin secretion [5]

McKenzie, P.M

Brand versus generic : Branded medications cost more than older or generic options