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Human neuroimaging studies demonstrate that GLP-1RAs influence brain activity during food cognition, supporting a role in pre-ingestive satiation
Rising case numbers expand the patient base needing effective, easier treatments like oral GLP-1 therapies
Van Guelpen B, Hultdin J, Johansson I, et al
Note: This is not medical advice
Oxidative stress, mitochondrial dysfunction and glutamate excitotoxicity may also interact as a feed-forward vicious cycle (Nguyen et al, 2011) : Our results conclusively demonstrate that not only glutamate excitotoxicity and/or oxidative stress alters mitochondrial fission/fusion, but that an imbalance in mitochondrial fission/fusion in turn leads to NMDA receptor upregulation and oxidative stress
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