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As with all GLP-1 agonists, long-term post-marketing surveillance will be essential to characterize the pancreatic safety profile with greater statistical precision, particularly for rare events such as acute pancreatitis (estimated background rate of approximately 35 per 100,000 person-years in the general population) and the theoretical concern about pancreatic cancer

Common : Nausea (up to 44%), vomiting, diarrhea, constipation Less common : Fatigue, dyspepsia, bloating, dizziness Rare : Cholelithiasis, acute pancreatitis Serious : Risk of thyroid tumors (animal data), kidney impairment due to dehydration Proper storage is critical to maintaining the products efficacy

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An earlier meta-analysis of 45 studies found no relationship between the use of six different GLP-1 drugs and acne cases

Managing Symptoms and Safety Concerns While waiting for the drug to clear your system, persistent vomiting and nausea can lead to severe dehydration and malnutrition