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Current clinical evidence from a meta-analysis of phase 2 and three studies of tirzepatide in participants with T2D indicates that tirzepatide treatment is not associated with an increased risk of MACE-4, a composite outcome comprising the four outcomes cardiovascular death, nonfatal myocardial infarction, nonfatal stroke, and hospitalization due to unstable angina (HR = 0.80
When patients lose weight on a GLP-1 receptor agonist and their blood pressure improves and their cholesterol gets better, the easy assumption is that the cardiovascular protection is just a downstream consequence of the weight loss
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Additionally, semaglutide has been approved for the regulation of blood sugar in diabetic patients
Electrolyte replacement is important, diarrhea depletes sodium, potassium, and magnesium
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