Neuropathologically, PD is defined by the gradual and selective destruction of dopaminergic neurons in the substantia nigra pars compacta (SNpc), resulting in a significant drop in striatal dopamine levels [5]
Pooled samples were loaded into two lanes per group for a total of 24 lanes across three 10X Chromium chips
GMP (Good Manufacturing Practice) is an FDA-mandated certification
Its multifunctional properties include the regulation of cellular osmolarity, modulation of calcium handling, support of mitochondrial activity, facilitation of bile acid conjugation, and participation in antioxidative pathways that protect cells from excessive reactive species (Huxtable, 1992)
Manach, C., Williamson, G., Morand, C., Scalbert, A