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Glia 62 , 608622 (2014)
Apoptosis inhibition further enhances these AHK-Cu benefits by downregulating Bax, a pro-apoptotic protein, and upregulating Bcl-2, an anti-apoptotic protein
Most before-and-after claims are unverified
Ferric citrate, on the other hand, antagonizes ferroptosis by activating the Nrf2 signal, promoting its nuclear translocation and binding to the antioxidant response element (ARE) in the GPX4 promoter region, which exponentially upregulates GPX4 expression (221)
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