Para a indstria, isso representa uma nova camada de exigncia no desenvolvimento de produtos: alm de nutritivos, precisam ser bem tolerados
Using GLP-1s at lower doses as part of integrated treatment is a logical extension of what I already do
Roth, C., Schwiete, C., Happ, K., Rettenmaier, L., Schenfeld, B., & Behringer, M
21 Given this critical findings, The ADA advises using GLP-1 RAs to treat type 2 diabetes in adults with MASH, citing histological benefits demonstrated in the mentioned phase 2 randomized controlled trials
Some recommend maintaining the highest tolerated dose to prevent weight regain, while others support gradual reduction with close monitoring and lifestyle changes