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To be clear, this is not an expansion of scope

Zhou et al., [60]

Adenovirus-mediated long-term overexpression of FGF21 in high-fat diet-induced obese mice suppresses hepatic and adipose inflammatory cell infiltration and activation (187)

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Moreover, we excluded patients and controls who suffered from neurodegenerative and neuroinflammatory disorders, such as chronic fatigue syndrome [54], Parkinsons or Alzheimers disease, multiple sclerosis, stroke, or systemic (auto)immune diseases such as diabetes mellitus, psoriasis, rheumatoid arthritis, inflammatory bowel disease and scleroderma, and liver and renal disease