The European Medicines Agencys (EMA) Pharmacovigilance Risk Assessment Committee concluded that no product label update was warranted, based on data from clinical trials, real-world safety monitoring, and electronic health records [45]
This means that while bloating is common, it is overwhelmingly manageable in clinical settings
However, the purpose of treating type 2 diabetes is not merely to lower levels of glycated hemoglobin, but to reduce the risk of the macrovascular and microvascular complications of the disease
Losing weight faster than this without medical supervision often leads to muscle loss, metabolic slowdown, and weight regain
Food and Drug Administration: FDA Approves Treatment for Serious Liver Disease Known as MASH Harvard Health Publishing: Diabetes and Obesity Drug Shows Promise for Fatty Liver Disease American Association for the Study of Liver Diseases: Why Are GLP-1 Agonists Being Used to Treat Patients With Nonalcoholic Fatty Liver Disease