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A specific example: a widely cited 2024 blog post from a telehealth competitor states "patients switching from Wegovy 2.4 mg should start Zepbound at 7.5 mg to maintain therapeutic effect." This is wrong for three reasons: It contradicts FDA-approved titration
They may or may not include updated dosing instructions
Research on the relationship between dosage and efficacy has not been well-established, thus further clinical studies are required to identify optimal dosage regimes for certain health effects with consideration of an individuals age, individual condition and health status
Your GP or specialist will work with you to determine the most appropriate duration based on your treatment goals, response to therapy, and ability to maintain improvements through lifestyle measures alone
However, Januvia requires dose adjustment in patients with renal impairment specifically, a reduction to 50 mg for eGFR 3044 and 25 mg for eGFR below 30
