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On the other hand, sterols are bile acid sequestrants and acyl coenzyme A cholesterol acyltransferase activity (ACAT) inhibitors and its consumption leads to lower levels of plasma LDL cholesterol (Jesch & Carr, 2017)
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doi:10.1186/s40200-016-0250-x
Explored as a possible aid for recovery and lean-mass preservation in frail or catabolic populations, though a Merck-sponsored Phase 2b trial in elderly hip-fracture patients (Adunsky et al., 2011, Archives of Gerontology and Geriatrics, PMID 21067829) was halted early over a cardiac safety signal rather than demonstrating a clear functional benefit
