Acknowledgements This study was supported by a grant from the Chung Shan Medical University (CSMU-INT-101-09), Taiwan
Similarly, in oncology, zinc-based nanomaterials have been used to induce ER stress and the UPR, culminating in immunogenic cell death and enhancing the efficacy of immune checkpoint blockade therapies 181,182
Notably, these advantages persisted irrespective of baseline kidney function, HbA1c levels, BMI, the timing of DM diagnosis, comorbidities and concurrent medication, including immunosuppressants (Fig
This broad-spectrum formulation binds to many toxins such as heavy metals, pesticides, herbicides, hormone mimics, food additives, mould, and microbes for removal from the body
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