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It may be that short-acting GLP-1RAs act more like endogenous GLP-1 and communicate to the brain primarily via the vagus nerve, whereas long-acting GLP-1RAs like liraglutide and semaglutide primarily access the brain directly
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Novo Nordisk frames the therapy as a potential first-in-class diabetes option and intends to discuss a regulatory pathway with authorities
& Wojtowicz, J
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