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If you use them for years, were talking about thousands of dollars
Common side effects (nausea, constipation) typically resolve within 2-3 weeks
10.1016/j.cmet.2017.09.019 13 BellD
The goal is to maintain a steady level of pain relief so you never hit that painful crash. By alternating the medications every 3 hours (each individual drug taken every 6 hours), you make sure that as one medication dips, the other is reaching its peak
At the same time, dismissing these compounds entirely ignores legitimate scientific inquiry
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