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Semaglutide with Intensive Behavioral Therapy (STEP 3) Wadden TA et al., JAMA 2021: Combined pharmacotherapy + behavioural therapy effect size
Think of the gelatin trick as training wheels, not the whole bike
If needed, it may be increased slowly over time based on response and tolerance
The individualized maintenance dose should balance efficacy, health benefits, and tolerability and therefore may not necessarily be the maximum approved dose
SGLT2 inhibitors are the mechanism of action for Jardiance and GLP-1 is the mechanism of action for Ozempic
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