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Because your body cannot make B12 on its own, you must get it from food, supplements, or medical injections
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To analyze this, we conducted rescue experiments by re-expressing wildtype TBC1D9B-HA or a GAP activity-defective point mutant with mutations in the arginine (R) and glutamine (Q) fingers 38,40 (i.e., R559A/Y592A/Q594A (TBC1D9B RYQ/AAA )) (see also Fig
72452-4.fp.png)
CASP9, Caspase 9
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