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Balance between on- and off-target effects of the dual GLP1/E agonist, and the concurrence of desensitization at very high doses, might contribute to this phenomenon
Patti, M
According to the researchers, Contrary to reports of increases in suicidal ideation with semaglutide, our analyses revealed a lower risk for both incidence and recurrence of suicidal ideation in patients prescribed semaglutide compared with non-GLP1R agonist anti-obesity and anti-diabetes medications. 20 If you look at the study a little bit deeper there was a decreased risk in [suicidal ideation] in women, men and along every racial group, said Catherine Varney, DO, obesity medicine director for UVA Health and an assistant professor of family medicine at the University of Virginia
GLP-1 is a hormone produced in the intestines in response to food intake
Care 8 , e001600 (2020)
