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Other reported side effects include: Headache Fatigue and weakness Dizziness (as discussed) Increased heart rate (usually a small increase but may require monitoring) Gallbladder disorders (including gallstones) Changes in taste Important safety warnings that require medical attention include: Pancreatitis (severe abdominal pain radiating to the back, with nausea and vomiting) Severe allergic reactions (difficulty breathing, swelling of face or throat) Mood changes or suicidal thoughts (seek urgent care and stop treatment if these occur) Kidney problems from dehydration (reduced urine output, swelling) Thyroid concerns (seek medical review for neck mass, voice changes, or persistent hoarseness

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DSIP appears to modulate multiple receptor systems and influence the hypothalamic-pituitary axis

Liu, H., Zhan, Y

Some pharmacies outside the US still compound it