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Niacin (Vitamin B3)
Mutations in the HMGCL gene result in HMG-CoA lyase deficiency, a disorder referred to as 3-hydroxy-3-methylglutaric aciduria
[57] This cascade alters cellular energy dynamics, ultimately triggering the influx of calcium into the cell, which prompts the exocytosis (release) of insulin-containing vesicles into the bloodstream
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