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(The FDA has received more than 700 adverse event reports tied to compounded GLP-1s, but its not clear if the events were caused by the drugs.) The companies also see compounders as a threat to their obesity drug sales, which are estimated to balloon to $100 billion a year by 2030

42 Compared to GLP-1, exenatide has nine extra residues in the C-terminal, which constitute a so-called Trp-cage structure, folding and shielding the Trp 25 indole ring from solvent exposure

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AOP enzymes contain the active center of metal ions with variable valence, which, depending on the conditions, act as both an oxidizing agent and a reducing agent [7]