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Researchers should keep vials sealed until preparation and allow cold materials to equilibrate before opening when condensation risk is present
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Such molecules can bind to proteins (which contain hundreds or even thousands of amino acids), altering these proteins function, and therefore serving as biochemical messengers
In cardiac models, Bock-Marquette et al., Nature 2004 reported that T4 activates integrin-linked kinase and Akt signalling, promoting cardiomyocyte survival, migration and improved function after coronary ligation in mice
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