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The MC1R activity still drives pigmentation, but the added MC4R activity is what produces the erectile/libido effects and the appetite suppression and nausea that Melanotan 2 is notorious for effects a MC1R-preferential molecule like Melanotan 1 does not share

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His research has found that GLP-1 given to fattened mice caused cells to cut back on glucose production, reducing oxidative stress, which can cause inflammation

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