No ones giving you a gold star for cramming 40 grams into breakfast if it ruins your afternoon
We always see efficacy go down with the biologics when we have very heavy patients
Lysine helps support healthy skin, connective tissue, immune function, and overall health through its role in collagen formation and protein synthesis. Daily supplementation provides nutritional support for individuals who may not obtain adequate lysine through diet alone.
Whilst this may result in less robust therapeutic effects, a tolerable lower dose that patients can maintain long-term often proves more beneficial than a higher dose that leads to discontinuation
To establish the T2DM model, after 8 weeks of HFD (10% lard, 20% sucrose, 2.5% cholesterol, 1% bile salt, and 66.5% regular diet), rats received the intraperitoneal (i.p.) injection of 35 mg/kg STZ (Sigma) after overnight fasting