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Under an inflammatory environment and oxidative stress, as obesity progresses, the increased secretion of pro-inflammatory cytokines and chemokines, such as monocyte chemotin-1, tumor necrosis factor (TNF) , and interleukin (IL)-6, lead to a low-grade inflammatory response throughout the body (65)
Wang J, Yin Z, Tang W, Cai X, Gao C, Zhang H, et al
Curcumin inhibits APAP-induced hepatocyte apoptosis by reducing the expression of pro-apoptotic genes Bax and caspase-3, inducing anti-apoptotic genes like Bcl-x1, and increasing the ratio of Bcl2/Bax (Li et al., 2013)
Steroids can affect growth in children
Compounding is a mechanism for meeting a genuine individual clinical need
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