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While most people can obtain sufficient B12 through their diet, certain groups are at higher risk of deficiency and may benefit from supplementation

They can always adjust your dose if needed

[9] Patients should be advised to contact their healthcare provider if they experience any severe or persistent side effects, such as difficulty breathing, chest tightness, severe rash, or dizziness

Decreased plasma nicotinamide and altered NAD(+) metabolism in glial cells surrounding [PMID: 39374707] Laboratory literature summary: Decreased plasma nicotinamide and altered NAD(+) metabolism in glial cells surrounding A plaques in a mouse model of neurodegeneration

For that fat to actually leave your body, you need to use it