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Macrophage polarization in pathology
Here, I propose to use the most cutting-edge sequencing technology and the high-resolution electrophysiology recording currently available to identify and characterize the cells in the MHb-IPN circuit that show robust transcriptional and functional plasticity in response to the opioid drug oxycodone (OxyContin)
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Mattson's laboratory observed that animals that were fasted or exercised had increased the number of mitochondria and increased the number of synapses in the animal's brain
