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Cells exposed to 16.8 mM glucose in the presence of 100 nM Exendin-4-Fc showed a significant increase in insulin mRNA level, as compared to those without Exendin-4-Fc, while cells exposed to 2.8 mM glucose only showed no significant change in insulin mRNA level with or without Exendin-4-Fc
Research in Archives of Biochemistry and Biophysics shows that TGF- decreases intracellular glutathione content in fibroblasts, triggering increased collagen I mRNA and protein production
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