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Earlier GLP-1R agonists could cross into the brain and do have effects on the mouse model of Alzheimers disease, but the newer drugs have been designed to stay in the blood for a very long time and do not really cross into the brain, said Hlscher

The reductions in systolic blood pressure were consistent across subgroups of participants in the study who were categorized by additional factors, including age, sex, body mass index, and hypertension-related risk factors

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PMID: 31 KohanDEFiorettoPTangWListJF