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Why DDIs Matter in Drug Discovery & Development Influence dose selection and labeling Drive clinical trial design Affect real-world safety Require early evaluation during ADME-Tox studies Understanding DDIs early prevents late-stage surprises
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Contact your GP or optometrist promptly if you experience: Sudden vision changes , including blurred vision, floaters (dark spots or strings), or flashes of light Progressive difficulty reading or recognising faces Dark or empty areas in your visual field Distorted vision , where straight lines appear wavy Eye pain or redness accompanied by vision changes Difficulty with night vision or colour perception If you experience sudden, painless vision loss in one or both eyes, this constitutes an ophthalmological emergency
In summary, future clinical trials should prioritize enrolling individuals at risk, followed by those in the early stages of the disease, as this offers a higher likelihood of demonstrating neuroprotective and disease-modifying effects
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