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5 At one time, it was theorized that there was a single hormone responsible for this activity, but it was discovered that two hormones secreted from the intestines are primarily responsible for the incretin effect, GLP-1 and glucose-dependent insulinotropic polypeptide (GIP)
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Understanding the pharmacological differences Before looking at the conversion chart, you need to understand why a direct milligram-to-milligram comparison between tirzepatide and semaglutide does not work
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