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I know you didn't mention that as an issue, but I feel there is some link between B12, cystic acne, mast cell dysfunction, gastroparesis and probably many other symptoms
In a number of experimental and clinical studies, Lipoic acid has now been shown to be useful in the treatment of such conditions as diabetes, ischemia-reperfusion damage, neurodegeneration, heavy-metal poisoning, radiation damage and HIV infection and may offer significant protection against stroke, heart disease and cataracts (Packer L et al., 1995)
"Toxicity of copper to the marine amphipod Allorchestes compressa in the presence of water-and lipid-soluble ligands"
10.1016/j.ijrobp.2011.09.020 180
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