For comparison, the improvement in glycemic control following bariatric surgery is of the same order, with a decrease in A1c varying between 1.8 and 3.5%
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doi: 10.1371/journal.pone.0067578 100 FarahLXValentiniVPessoaTDMalnicGMcDonoughAAGirardiAC
As mentioned, AOD-9604 is a modified version of the hGH 177-191 fragment, with the only modification being the addition of the amino acid tyrosine at the N-terminus [6]
Most human studies rely on small sample sizes, short intervention periods, and subjective appetite or liking scales, while lacking objective gustatory measures such as taste-threshold testing or electrogustometry (153, 173, 180, 181)