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The proposed net effect in experimental systems is a shift in energy substrate utilisation without the hyperglycaemic liability that pure glucagon agonism would carry alone

Endocrine Reviews, 24 (6), 737-764

The dosage and duration of treatment may vary depending on nutritional status, underlying medical condition, and individual response to therapy

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"Glucagon-like peptide-1 receptor agonists activate rodent thyroid C-cells causing calcitonin release and C-cell proliferation." Endocrinology , 151(4), 1473-1486