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The ACOG 2024 Contraception in Women With Obesity guideline recommends intrauterine devices or subdermal implants as first-line options in patients receiving weight-loss pharmacotherapy who do not desire pregnancy

2010 Mar;35(3):437-43

Current analyses indicate that the cost of tirzepatide is not regarded as cost-effective at its current price level, requiring a notable decrease of about 30.5% to meet cost-effectiveness criteria

Thrombus formation was more pronounced in mice transplanted with bone marrow deficient in functional GLP-1R (Glp1r/) compared to those with wild-type bone marrow, with these effects being dependent on nitric oxide [57]