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Its generally safe in moderation, but there are concerns with drinking large amounts and with regular consumption during pregnancy
Cycle 2 to 4 weeks on, 2 to 4 weeks off
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Also, since you need stomach acid to absorb B12, long-term use of acid-suppressing proton pump inhibitors (such as Nexium, etc.) can lead to B12 deficiency, as can chronic intestinal conditions such as Crohns disease, celiac disease, and intestinal parasites
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