PE135010: β-GalNAc-PEG3-Thiol Pack Size:10 mg Fmoc-Thr([Gal β(1-4)Glc]Ac7)-OH

Fmoc-Thr([Gal β(1-4)Glc]Ac7)-OH

/ MUC1(126-149)-STn(131) / Mucin1

2-(Acetylthio)ethyl β-D-glucopyranoside

6-tri-O-acetyl-α-D-galactopyranosyl)-L-Serine

66 / An Fmoc-protected L-threonine building block carrying a β-D-GlcNAc residue

PE135010: β-GalNAc-PEG3-Thiol Pack Size:10 mg Fmoc-Thr([Gal β(1-4)Glc]Ac7)-OHC14H27NO8S 369. 43 A D N acetylgalactosamine (GalNAc) ligand equipped with a free thiol through a hydrophilic PEG3 spacer. The thiol reacts with maleimides to form stable thioether conjugates or with other thiols to form disulfide bonds; it is also compatible with thiol gold chemistry for surface immobilization. This compound enables the construction of hepatocyte targeted therapeutics and research tools that exploit the asialoglycoprotein receptor