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12 / An Fmoc-protected L-serine building block carrying a Neu5Acα2-6GalNAcα disaccharide
TSA 840-d6
The installed glycan is chitobiose (GlcNAcβ1-4GlcNAcβ-N-Asn)
The terminal azide can be covalently coupled to alkyne partners via copper-catalyzed azide-alkyne cycloaddition (CuAAC)
Fmoc-Ser(β-D-Gal(1-3)[β-D-GlcNAc(1-6)]-α-D-GalNAc)-OH
AG525005: β-D-Glc-Ethyl-Thioacetate Pack Size:50 mg 12 / An Fmoc-protected L-serineC10H18O7S 282. 31 A D glucose ligand equipped with a thioacetate protected thiol linker through a short ethyl spacer. The thioacetate serves as a masked thiol that can be deprotected under mild basic or hydrolytic conditions to reveal a free thiol, which can then be reacted with maleimides to form thioether conjugates or with thiol modified substrates to form disulfide bonds. This compound provides a D glucose building block for glycoconjugate
