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Beyond the absolute contraindications, several situations call for heightened caution in the class framing and are firmly a clinicians domain: a history of pancreatitis or symptomatic gallstones, significant gastrointestinal motility disorders (such as gastroparesis, which slowed gastric emptying can worsen), diabetic retinopathy that is not stabilized, severe renal impairment where dehydration from GI side effects raises risk, and any concurrent use of insulin or a sulfonylurea, where the additive glucose-lowering can produce hypoglycemia

For example, it reacts with the NO radical, and makes toxic peroxynitrite

Updated June 2024.

This helps prevent irritation and ensures better medication absorption

Ostad can recommend chemical peels or lasers like PicoWay and Fraxel