Overall, the benefit-risk profile supports broad use of GLP-1-based therapies in MASLD across most patient subgroups, with individualized monitoring plans for high-risk populations
An interesting question is whether one of these hormones contributes more to tirzepatides effects than the other
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Tesamorelin (Egrifta SV) is approved to reduce excess abdominal fat in HIV-associated lipodystrophy and has formal prescribing information, warnings, and monitoring expectations
For patients with persistent symptoms despite optimal thyroid hormone replacement, further investigation may be warranted to exclude other conditions such as coeliac disease , vitamin D deficiency, iron deficiency anaemia, or depression, all of which are more common in individuals with autoimmune thyroid disease