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These increases happen at four-week intervals, but the timeline can be extended if needed

Patients should seek urgent medical attention for severe persistent abdominal pain (especially if radiating to the back), persistent vomiting, jaundice, fever, inability to pass stool/gas, or abdominal distension, which could indicate serious complications such as pancreatitis, gallbladder disease, or intestinal obstruction

Additionally, dietary adherence, physical activity levels, and concurrent medications can influence perceived effectiveness over time

The benefits are not stored

Cardiovascular safety of vildagliptin in patients with type 2 diabetes: a European multi-database, non-interventional post-authorization safety study