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Key findings include enhanced phosphorylation of Src, Caveolin-1, and eNOS, with the vasodilation effect being abolished by nitric oxide inhibitors
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The solution is packaged in a 20ml vial to facilitate ease of use and accurate measurements
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If patients are to start NASCOBAL before having tolerated cyanocobalamin parenterally, consider administering an intradermal test dose of parenteral vitamin B12 to patients suspected of cyanocobalamin hypersensitivity [see Dosage and Administration (2.1)]
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