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Joint destruction : Pannus erodes articular cartilage (via matrix metalloproteinases) and subchondral bone (via RANKL-stimulated osteoclasts), leading to marginal erosions visible on X-ray and MRI

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doi:10.7326/0003-4819-146-2-200701160-00005

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J Alzheimers Dis 48:591595 Louwerse ES, Weverling GJ, Bossuyt PM, Meyjes FE, de Jong JM (1995) Randomized, double-blind, controlled trial of acetylcysteine in amyotrophic lateral sclerosis

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