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The disulfide within the active site is subsequently reduced through a glutathionylated intermediate by in total two molecules GSH leading to the release of glutathione disulfide (GSSG)

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Br J Pharmacol 92(2):457468 Holger JS, Engebretsen KM, Stellpflug SJ, Cole JB, Cooper AC, Harris CR (2010) A consecutive case series (abstract)

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