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A key paper published by Unger and Orci in 1975 helped to intensify research into the molecule (Unger, Orci)
Depending on the length of the gap, a provider may resume at the previous dose or step back down to reduce side effects
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Relative mRNA expression of Gclm (p = 0.0026), Hmox1 , Nqo1 , and Slc7a11 (d) and representative immunohistochemistry of indicated proteins (e) in Gclc WT and Gclc KO tumors (n = 6 representative from 3 independent experiments)
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