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Zhou J, Li Q, Cao Y
Glutathione also assists in enzymatic reactions and helps other antioxidants, like vitamin E, return to their active form to continue working as antioxidants
Moreover, vitamin D upregulates TRAF3 expression to inhibit the noncanonical NF-B2 pathway, alleviating the inflammatory state in end-stage renal disease (ESRD) patients and animal models (22)
TNF--induced necroptosis causes damage to cerebral endothelial cells in blood vessels, neuroinflammation, and dysregulation of astrocyte Kir4.1 [108, 109]
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