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Beyond glycemic effects, GLP-1 medications act on appetite regulation centers in the hypothalamus, promoting satiety and reducing hunger signals
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Tirzepatides 20-week escalation to max dose gives the body more time to adjust at each step, which may reduce the intensity of side effects during the transition period
That dual action is what gives it an edge over other weight loss medications
Gastrointestinal side effects Digestive symptoms are the most common problem
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