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Its primary mechanism is activating VEGFR2 a receptor that triggers the formation of new blood vessels (angiogenesis)
doi:10.1016/0928-4257(93)90038-uPMID:8298609 [9] Klicek R, Sever M, Radic B, et al
Huang L, Lu J, Cerqueira B, Liu Y, Jiang Z, Duong T
These reactions typically resolve with continued use as the skin acclimates, or with dose reduction
Still got the dead arm and a fair bit of stinging but not the burning pain - so a good result
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