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This phenomenon might result in an increased presence of senescent cells, defined as cells that cease to divide but fail to die, thereby contributing to the aging of the cell population
This represents an exposure of approximately 2- and 6-times a clinical dose of 2,000 mg, based on body surface area (mg/m2) for rats and rabbits, respectively
Supernatants of cells or tissues were stored at 80 C until analysis
Statistically, stopping GLP-1 therapy can lead to weight regain if those habits arent solidified [intermountainhealthcare.org]
Clin Sci (Lond) 132(15):16991709
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