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This section delves into strategies aimed at mitigating these risks, ensuring patient safety, and maintaining therapeutic efficacy

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They are engineered to bind to the same receptors as natural GLP-1 and resit breakdown by DPP-4 allowing them to remain active for much longer, hours to weeks longer

The doses used in trials were around 500ug/kg, which means a 100kg person was receiving 50mg of the peptide daily. $50 million in research and development down the drain for a promising product that was no longer a viable pharmaceutical product

As the body metabolizes stored glycogen, bound water is released and excreted through the kidneys, potentially increasing urine output temporarily