Short-term effects (first 12 weeks) Injection-site irritation : redness, itching, or swelling Headaches or nausea : usually mild and temporary Fatigue or drowsiness : some people feel extra tired at the start Water retention or bloating : often resolves as your body adjusts Occasional but less common effects Joint stiffness or aches Tingling or numbness (paresthesia, often in the hands or feet) Increased appetite These usually fade as your body adapts, but if they linger, its worth checking in with your provider
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To minimise reactions: ensure proper injection technique, rotate sites consistently, avoid injecting into areas with skin conditions, and never reuse needles
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However, the intramuscular injection)route was the "top-ranked statistically" but without clinical significance